Global Bio-Detection HLS-HLD Technologies and Markets – 2010-2014
| November 2009 |
Publication: Q4 2009, Pages: 325, Figures: 134, Tables: 93

Despite eight years of research and development, and program implementation, at a cost of more than $49.7 billion (in the U.S. alone), virtually all significant targets are as vulnerable to biological warfare today as they were in September 2001.
In the words of President Obama: “Just as we must guard against the spread of nuclear terrorism, it’s time for a comprehensive effort to tackle bio-terror. ..we know that the successful deployment of a biological weapon – whether it is sprayed into our cities or spread through our food supply – could kill tens of thousands of Americans and deal a crushing blow to our economy.”
Homeland Security Research Corporation (HSRC) forecasts that, led by the US, Germany, France, China, Japan and India, the cumulative global bio-detection market (systems, service and upgrades and R&D) will grow from $2.3 billion in 2009 to $4.9 billion in 2014 at a CAGR of 16%.
Developed using HSRC’s tested methodology, the report delves into:
- Global market by expenditure segments: systems, upgrade and service segments
- Global market by technology generation: first, second and third
- Global market by installation segments: indoor, outdoor, hand-held and mobile labs
- Leading global bio-security projects
- Current and pipeline technologies: e.g..advanced collectors-concentrators, reagent-less triggers, DNA-based diagnostics, antigen/anti-body methods, signal analysis algorithms
- Competitive analysis: e.g. barriers to entry, barriers to substitution, competitive rivalry
- Regional market analysis: e.g. USA, UK, Germany, France, Italy, Singapore, Spain China, Taiwan, Japan, India, Middle East
- Business opportunities: e.g. emerging threats, human and animal sentinel surveillance, reagent-less detection assays, IC3
- Market drivers and inhibitors: i.e. government fears and government funds, inadequate detection technologies, strong public and media support for bio-defense
| 1. Introduction | 27 |
| 1.1. Scope | 27 |
| 1.2. Terms of Reference | 27 |
| 1.3. Methodology | 28 |
| 1.4. Who is This Report For? | 31 |
| 2. Executive Summary | 33 |
| 2.1. Main Findings | 33 |
| 2.2. Main Conclusions | 38 |
| 2.3. Global Bio-Detection Market Forecast – 2010-2014 | 42 |
| 2.3.1. Global Systems, Service & Upgrade Markets – 2010-2014 | 42 |
| 2.3.2. Markets by Countries & Regions – 2010-2014 | 44 |
| 2.3.3. Markets by Outdoor, Indoor, Hand-Held and Mobile Lab – 2010-2014 | 46 |
| 2.3.4. Systems Market by Technology Generation – 2010-2014 | 47 |
| 2.3.5. Service & Upgrade Market by Generation – 2010-2014 | 49 |
| 2.4. Business Opportunities | 51 |
| 2.4.1. Bio-Surveillance, Detection & Bio-forensics Business Challenges – 2010-2014 | 52 |
| 2.5. Technology Outlook | 56 |
| 3. Bio-Terror | 57 |
| 4. Forty Countries: Bio-Security Status Review | 58 |
| 4.1. Background | 58 |
| 4.1.1. Forty Countries Bio-Technology & Bio-Defense Performance Score | 58 |
| 5. Market Drivers | 60 |
| 6. Market Inhibitors | 62 |
| 7. Bio-Detection Industry Competitive Analysis | 63 |
| 8. Industry SWOT Analysis | 64 |
| 8.1. Scope | 64 |
| 8.2. SWOT Analysis | 65 |
| 9. The Bio-Detection Process | 66 |
| 9.1. Sampling the Environment | 66 |
| 9.2. Bio-Detectors in a Multitude of Ambient Settings | 67 |
| 9.3. Bio-Detection Triggering | 67 |
| 9.4. Sample Collection | 67 |
| 9.5. Bio-Particle Detectors | 68 |
| 9.6. Bio-Agent Identification | 69 |
| 10. Bio-Detection Technological Challenges | 70 |
| 10.1. Challenge 1 – Detection of Small Particle Concentration | 71 |
| 10.2. Challenge 2 – Bio-Background Suppression | 72 |
| 10.3. Challenge 3 – Expensive Reagents | 72 |
| 10.4. Challenge 4 – Expensive Equipment Maintenance | 72 |
| 10.5. Challenge 5 – Adapting Equipment to Changing Environments | 73 |
| 10.6. Challenge 6 – Dealing With Emerging Threats | 73 |
| 11. Present and Pipeline Bio-Detection Technologies | 74 |
| 11.1. Bio-Detection – Core Technologies Comparison | 74 |
| 11.2. Collector/Concentrator Core Technologies | 77 |
| 11.3. Cyclone Collectors | 77 |
| 11.4. Variable Particle-Size Impactor | 78 |
| 11.5. Virtual Impactors | 78 |
| 11.6. Impingers | 79 |
| 11.7. Reagent-less Trigger Core Technologies | 79 |
| 11.7.1. Flow Cytometry | 80 |
| 11.7.2. Particle Sizing | 81 |
| 11.7.3. Gas Chromatography | 81 |
| 11.7.4. Trigger Technologies – Drivers | 82 |
| 11.7.5. Trigger Technologies – Inhibitors | 82 |
| 11.8. DNA Based Diagnostic Core Technologies | 83 |
| 11.8.1. Overview of DNA-Based Detection | 83 |
| 11.8.2. Polymerase Chain Reaction (PCR) | 83 |
| 11.8.3. DNA / RNA Microarrays | 88 |
| 11.8.4. DNA Technology Drivers | 90 |
| 11.8.5. DNA Technology Inhibitors | 90 |
| 11.9. Antibody-Antigen Diagnostic Core Technologies | 90 |
| 11.9.1. Overview of Antibody-Antigen Reaction | 90 |
| 11.9.2. Hand-Held Immuno-Chromatographic Assays (HHA) | 91 |
| 11.9.3. Magnetic Microbead-Base Assays | 92 |
| 11.9.4. Microfluidic Devices – “Lab on a Chip” | 92 |
| 11.9.5. Fluorescence Imaging | 93 |
| 11.9.6. Electrochemical-Luminescence (ECL) | 93 |
| 11.9.7. Antibody/Antigen Technology – Drivers | 93 |
| 11.9.8. Antibody/Antigen Technology – Inhibitors | 93 |
| 11.1. Signal Analysis Algorithms | 94 |
| 11.10.1. Clustering / Classifier Algorithms | 94 |
| 11.10.2. Image Analysis Algorithms | 94 |
| 11.10.3. Decision Algorithms | 94 |
| 11.10.4. Drivers | 94 |
| 11.10.5. Inhibitors | 95 |
| 11.11. Rapid Microbiological Technologies | 95 |
| 12. Bio- Detection – Analysis by Application | 97 |
| 12.1.1. Application 1 – Emergency Responder Hand-Held Detectors | 97 |
| 12.1.2. Application 2 – Emergency Responder Mobile Labs | 98 |
| 12.1.3. Application 3 – Indoor Standoff Detectors | 99 |
| 12.1.4. Application 4 – Outdoor Standoff Detectors | 100 |
| 13. Global Bio- Detection Market – 2010-2014 | 101 |
| 13.1. The Global Market Overview | 101 |
| 13.2. Markets by Systems, Upgrade and Service Segments – 2010-2014 | 102 |
| 13.3. Global Market by Countries & Regions – 2010-2014 | 104 |
| 13.4. Global Systems Market by Technological Generation – 2010-2014 | 106 |
| 13.5. Global Systems Market by Indoor, Outdoor, Hand-Held and Mobile Labs Segments – 2010-2014 | 109 |
| 13.6. Global Service & Upgrade Market by Technological Generation – 2010-2014 | 111 |
| 13.6.1. Global Service and Upgrade Business by Technological Generation – 2010-2014 | 111 |
| 13.6.2. Global Service & Upgrade Market by Indoor, Outdoor, Hand-Held and Mobile Labs Segments – 2010-2014 | 113 |
| 14. US Bio-Detection Market – 2010-2014 | 116 |
| 14.1. Leading Bio-Security Projects | 116 |
| 14.1.1. Project BioWatch | 116 |
| 14.1.2. Project BioSense | 117 |
| 14.1.3. Project BioShield | 118 |
| 14.2. US Bio-Defense Background & Analysis | 118 |
| 14.3. US Bio-Defense Funding | 121 |
| 14.3.1. DHHS Bio-Defense Missions and Funding | 123 |
| 14.3.2. DHS Bio-Defense Missions and Funding | 124 |
| 14.3.3. DOD Bio-Defense Missions and Funding | 124 |
| 14.3.4. DOA Bio-Defense Missions and Funding | 125 |
| 14.3.5. EPA Bio-Defense Missions and Funding | 125 |
| 14.3.6. Other Bio-Defense Missions and Funding | 125 |
| 14.4. The Obama Administration Bio-Defense Strategy | 126 |
| 14.5. Market Drivers | 128 |
| 14.6. Market Inhibitors | 128 |
| 14.7. US Bio-Detection Systems Market – 2010-2014 | 129 |
| 14.7.1. Sales by Generation Forecast | 129 |
| 14.7.2. US Bio-Detection Systems Market by Modality Forecast | 131 |
| 14.8. US Outdoor Standoff Bio-Detection Systems Market – 2010-2014 | 133 |
| 14.8.1. Sales Outlook | 133 |
| 14.9. US Indoor Bio-Detection Systems Market – 2010-2014 | 135 |
| 14.9.1. Indoor Market Outlook | 136 |
| 14.1. US Hand-Held Detection Systems Market – 2010-2014 | 137 |
| 14.10.1. Hand-Held Detection Systems Market Outlook | 137 |
| 14.11. US Mobile Bio-Detection Labs Market – 2010-2014 | 139 |
| 14.11.1. Market Outlook | 139 |
| 14.12. US Service Business – 2010-2014 | 141 |
| 14.12.1. Service & Upgrade Business by Modality – 2010-2014 | 141 |
| 14.12.2. Service Business by Generation – 2010-2014 | 143 |
| 15. The UK, Germany, France, Italy and Spain HLS-HLD Bio-Detection Market | 145 |
| 15.1. The European Union | 145 |
| 15.1.1. The European Union Bio-Defense Background | 145 |
| 15.1.2. EU Program of Cooperation on Preparedness and Response to Biological and Chemical Agent Attacks (BICHAT) | 147 |
| 15.1.3. EU Bio-Defense Research Programs | 148 |
| 15.2. The UK | 150 |
| 15.2.1. Bio-Defense Strategy | 150 |
| 15.2.2. Main Bio-Defense Initiatives | 151 |
| 15.3. Germany | 153 |
| 15.3.1. Bio-Defense Strategy | 153 |
| 15.3.2. Main Bio-Defense Initiatives | 154 |
| 15.3.3. Bio- Detection R&D Projects | 155 |
| 15.4. France | 158 |
| 15.5. Italy | 159 |
| 15.6. Spain | 160 |
| 15.7. Market Drivers | 160 |
| 15.8. Market Inhibitors | 161 |
| 15.9. UK, Germany, France, Italy and Spain Bio-Detection Systems Market – 2010-2014 | 161 |
| 15.9.1. Sales by Technology Generations Forecast | 161 |
| 15.9.2. Sales by Modality Forecast | 163 |
| 15.1. UK, Germany, France, Italy and Spain Outdoor Standoff Bio-Detection Systems Market Forecast – 2010-2014 | 165 |
| 15.10.1. Systems Market Outlook | 166 |
| 15.11. UK, Germany, France, Italy and Spain Indoor Bio-Detection Systems Market – 2010-2014 | 167 |
| 15.11.1. Systems Market Outlook | 168 |
| 15.12. UK, Germany, France, Italy and Spain Hand-Held Detection Systems Market – 2010-2014 | 169 |
| 15.12.1. Systems Market Outlook | 170 |
| 15.13. UK, Germany, France, Italy and Spain Mobile Bio-Detection Labs Market – 2010-2014 | 172 |
| 15.13.1. Market Outlook | 172 |
| 15.14. UK, Germany, France, Italy and Spain Service Business – 2010-2014 | 174 |
| 15.14.1. Service & Upgrade Business by Modality – 2010-2014 | 174 |
| 15.14.2. Service Business by Generation – 2010-2014 | 176 |
| 16. China, Taiwan, Japan, India and Middle East HLS-HLD Bio-Detection Market | 179 |
| 16.1. Asian Countries Bio- Defense Background | 179 |
| 16.2. Japan | 179 |
| 16.3. China | 181 |
| 16.4. Taiwan | 182 |
| 16.5. India | 183 |
| 16.6. Singapore | 184 |
| 16.7. Middle East | 185 |
| 16.8. Market Drivers | 185 |
| 16.9. Market Inhibitors | 186 |
| 16.1. China, Taiwan, Japan, India and Middle East Bio-Detection Systems Market – 2010-2014 | 186 |
| 16.10.1. Sales by Technology Generation – 2010-2014 | 186 |
| 16.10.2. Market by Modality – 2010-2014 | 188 |
| 16.11. China, Taiwan, Japan, India and Middle East Bio-Detection Outdoor Systems Market – 2010-2014 | 190 |
| 16.11.1. Sales Outlook | 190 |
| 16.12. China, Taiwan, Japan, India and Middle East Bio-Detection Indoor Systems Market – 2010-2014 | 192 |
| 16.12.1. Market Outlook | 192 |
| 16.13. China, Taiwan, Japan, India and Middle East Hand-Held Detection Systems Market – 2010-2014 | 194 |
| 16.13.1. Market Outlook | 195 |
| 16.14. China, Taiwan, Japan, India and Middle East Bio-Detection Mobile Labs Market – 2010-2014 | 196 |
| 16.14.1. Market Outlook | 196 |
| 16.15. China, Taiwan, Japan, India and Middle East Service Business – 2010-2014 | 198 |
| 16.15.1. Service & Upgrade Business by Modality – 2010-2014 | 198 |
| 16.15.2. Service Business by Generation – 2008-2014 | 200 |
| 17. The Rest of the World HLS-HLD Bio-Detection Market | 203 |
| 17.1. ROW: Bio-Defense Background | 203 |
| 17.1.1. Russia and CIS | 203 |
| 17.1.2. Russian Government Bio-Security Initiatives | 204 |
| 17.1.3. International Science and Technology Center (ISTC) | 205 |
| 17.1.4. Canada | 206 |
| 17.1.5. Australia | 207 |
| 17.2. Market Drivers | 207 |
| 17.3. Market Inhibitors | 208 |
| 17.4. ROW Bio-Detection Systems Market – 2010-2014 | 208 |
| 17.4.1. Sales Forecast by Generation | 208 |
| 17.4.2. Market by Modality Forecast | 210 |
| 17.5. ROW Outdoor Bio-Detection Systems Market – 2010-2014 | 212 |
| 17.5.1. Sales Outlook | 212 |
| 17.6. ROW Indoor Bio-Detection Systems Market – 2010-2014 | 214 |
| 17.6.1. Market Outlook | 214 |
| 17.7. ROW Hand-Held Detection Systems Market – 2010-2014 | 216 |
| 17.7.1. ROW Market Outlook | 216 |
| 17.8. ROW Mobile Bio-Detection Labs Market – 2010-2014 | 218 |
| 17.8.1. Market Outlook | 218 |
| 17.9. ROW Service Business – 2010-2014 | 219 |
| 17.9.1. ROW Service & Upgrade Business by Modality | 219 |
| 17.9.2. Service Business by Generation – 2010-2014 | 221 |
| 18. Bio-Detection Business Opportunities – 2010-2014 | 224 |
| 18.1. Historical Perspective: A Market Waiting for Transition | 224 |
| 18.1.1. The Current and Future HLS Bio-Defense Strategy for Detection | 224 |
| 18.1.2. Factors Affecting Biological Detectors Deployment and Technologies – 2010-2014 | 225 |
| 18.1.3. Biological Detection Technology Timeline – 1992-2014 | 226 |
| 18.2. Business Opportunities for Next Generation HLS Bio-Detection Systems | 228 |
| 18.2.1. Business Opportunity 1 – Emerging Threats | 228 |
| 18.2.2. Business Opportunity 2 – Human Sentinel Surveillance System | 229 |
| 18.2.3. Business Opportunity 3 – Animal Sentinel Surveillance System | 229 |
| 18.2.4. Business Opportunity 4 – Biological IC3 – Biological Threat Assessment Intelligence Command, Control, and Communication Infrastructure | 230 |
| 18.2.5. Business Opportunity 5 – Reducing False Alarms – Less False Positives and False Negatives | 230 |
| 18.2.6. Business Opportunity 6 – Reducing Cost – Minimizing Use of Non-Reusable Reagents | 230 |
| 18.3. Outdoor Standoff Biological Detectors | 231 |
| 18.3.1. Business Opportunity 7 – Bio-agent Autonomous Networked Detectors (BAND) | 231 |
| 18.3.2. Business Opportunity 8 – Rapid Automated Biological Identification System (RABIS) | 232 |
| 18.3.3. Business Opportunity 9 – First Responder Portable Hand-Held Detector | 232 |
| 18.3.4. Business Opportunity 10 – First-Responder Mobile Biological Detection Station | 233 |
| 18.3.5. Business Opportunity 11 – Regional Automatic Detector – Outdoor Standoff Detectors | 233 |
| 18.3.6. Business Opportunity 12 – Networked Automatic Detector – Indoor Standoff Detectors | 234 |
| 18.3.7. Business Opportunity 13 – External Dissemination of Bio-Agent Detection | 235 |
| 18.3.8. Business Opportunity 14 – Internal Dissemination of Bio-Agent | 235 |
| 18.4. Other Bio-Detection Technologies – Business Opportunities | 236 |
| 18.4.1. Business Opportunity 15 – “Lab on a Chip” – Miniature Detection Devices | 236 |
| 18.4.2. Business Opportunity 16 – Reagent-less Specific Detection Assays | 237 |
| 18.4.3. Business Opportunity 17 – Laser-Induced Breakdown Spectroscopy (LIBS) | 237 |
| 18.4.4. Business Opportunity 18 – Raman Spectroscopy-based Reagent-less Detection | 237 |
| 18.5. Future Technologies and Systems | 238 |
| 19. Bio-Defense U.S. Federal R&D Funding – 2010-2014 | 239 |
| 19.1. Summary & Outlook | 239 |
| 19.2. Bio-Defense Federal R&D Funding Forecast – 2010-2014 | 240 |
| 19.2.1. Department of Homeland Security Bio-Security R&D | 241 |
| 19.2.2. Department of Defense Bio-Security R&D | 242 |
| 19.2.3. Department of Health and Human Services Bio-Security R&D | 243 |
| 19.2.4. Other Agencies Bio-Security R&D | 244 |
| 19.3. HLS-HLD Bio-Detection R&D Funding – Drivers | 245 |
| 19.4. HLS-HLD Bio-Detection R&D Funding – Inhibitors | 246 |
| 19.5. Department of Homeland Security – Biological Detection HLS Technologies R&D Programs | 246 |
| 19.5.1. Surveillance and Detection R&D | 246 |
| 19.5.2. Rapid Development for Sensors for Novel Threat Agents | 247 |
| 19.5.3. Cross Correlation of Environmental Biological Sensors and Human Illness | 247 |
| 19.5.4. Facility Airborne Biological Toxin Alarm System (FABTAS) | 247 |
| 19.5.5. Field-Deployable Detection Technology for the Identification of Biological Toxins | 247 |
| 19.5.6. Forensics | 247 |
| 19.6. Defense Advanced Research Project Agency (DARPA) – Biological Detection HLS Technologies R&D Programs | 248 |
| 19.6.1. Hand-held Isothermal Silver Standard Sensor (HISSS) | 248 |
| 19.6.2. Triangulation Identification for Genetic Evaluation of Biological Risk (TIGER) | 248 |
| 19.6.3. Spectral Sensing of Bio-Aerosols (SSBA) | 249 |
| 19.6.4. Threat Agent Cloud Tactical Intercept Countermeasure (TACTIC) | 249 |
| 19.6.5. Immune Buildings | 249 |
| 19.7. Chemical Biological Defense Program (CBDP) – Biological Detection HLS Technologies R&D Programs | 250 |
| 19.7.1. Project CB1 – Biological Defense (Basic Research) – Detection | 250 |
| 19.7.2. Project CB2 – Biological Defense (Applied Research) – Detection | 251 |
| 19.7.3. Project CB3 – Biological Defense (ATD) – Detection | 251 |
| 19.7.4. Project CA5 Contamination Avoidance (SDD) | 251 |
| 19.8. Technical Support Working Group (TSWG) – Biological Detection HLS Technologies R&D Programs | 253 |
| 19.8.1. Real-Time Biological Aerosol Detection | 253 |
| 20. Vendors | 254 |
| 20.1. 20/20 GeneSystems Inc. | 254 |
| 20.2. Advnt Biotechnologies | 254 |
| 20.3. Agilent Technologies | 255 |
| 20.4. Alexeter Technologies | 256 |
| 20.5. ANP Technologies, Inc. | 257 |
| 20.6. BAS – Biological Alarm Systems Ltd. (Israel) | 257 |
| 20.7. BD Biosciences Immunocytometry Systems | 259 |
| 20.8. Bertin Technologies | 259 |
| 20.9. BioDefense Corporation | 260 |
| 20.1. BioDETECT AS | 261 |
| 20.11. BioSentinel Pharmaceuticals LLC | 262 |
| 20.12. 3M Microbiology (Biotrace International, Ltd.) | 263 |
| 20.13. BioTraces, Inc. | 263 |
| 20.14. BioVeris Corporation | 264 |
| 20.15. Biral | 265 |
| 20.16. Cepheid | 265 |
| 20.17. Commonwealth Biotechnologies, Inc. | 266 |
| 20.18. Dycor Technologies Ltd. | 266 |
| 20.19. Environics Oy | 267 |
| 20.2. Evogen, Inc. | 269 |
| 20.21. General Dynamics Canada | 270 |
| 20.22. GenPrime, Inc. | 271 |
| 20.23. Groton Biosystems | 272 |
| 20.24. Haztech Systems, Inc. | 272 |
| 20.25. Idaho Technology, Inc. | 273 |
| 20.26. JMAR Technologies, Inc. | 274 |
| 20.27. New Horizons Diagnostics | 275 |
| 20.28. Proengin | 276 |
| 20.29. QTL Biodetection | 276 |
| 20.3. Research International | 277 |
| 20.31. Response Biomedical | 278 |
| 20.32. Roche Applied Science | 278 |
| 20.33. Smiths Detection | 279 |
| 20.34. Tetracore, Inc. | 281 |
| 21. Prices of Bio-Detection Equipment | 283 |
| 22. Pricing Outlook – 2010-2014 | 286 |
| 23. Bio-Detection – Economic Considerations | 287 |
| 24. Bio-Detection – Personnel Considerations | 288 |
| 25. Appendix A: The Threat of Bio-Terror | 289 |
| 25.1. Biological Terror | 289 |
| 25.2. Bio-Weapons – Historical Perspective | 290 |
| 25.3. Biological Terror – Bacterial Agents | 292 |
| 25.3.1. Anthrax | 292 |
| 25.3.2. Cholera | 293 |
| 25.3.3. Plague | 294 |
| 25.3.4. Tularemia | 295 |
| 25.4. Biological Terror – Viral Agents | 296 |
| 25.4.1. Smallpox | 296 |
| 25.4.2. Hemorrhagic Fever Viruses | 297 |
| 25.4.3. Venezuelan Equine Encephalitis | 299 |
| 25.5. Biological Terror – Rickettsiae Agents | 300 |
| 25.5.1. Q Fever | 301 |
| 25.5.2. Typhus | 301 |
| 25.6. Biological Terror – Toxins | 302 |
| 25.6.1. Botulinum Toxin | 302 |
| 25.6.2. Ricin | 303 |
| 25.6.3. Saxitoxin | 303 |
| 25.6.4. Staphylococcal Enterotoxin B (SEB) | 304 |
| 26. Appendix B: Bio-Detection – Patent Review | 305 |
| 26.1. Scope | 305 |
| 26.2. Bio-Detection Patents | 305 |
| 27. Appendix C: Legal Issues | 317 |
| 27.1. International / European Legislation / Agreements | 317 |
| 27.1.1. The Biological and Toxin Weapons Convention (BTWC) 1972 | 317 |
| 27.2. U.S. Bioterrorism Legislation | 322 |
| 27.3. The European Treaties & Legislation | 325 |
| 27.3.1. EU Program of Cooperation on Preparedness and Response to Biological and Chemical Agent Attacks (BICHAT) | 325 |
List of Figures
| Figure 1 – US Federal Cumulative HLS-HLD Bio-Defense Funding – 2001-2009 [$Million], by Agency |
| Figure 2 – Bio-Detection Strategy – Three Pillars |
| Figure 3 – Bio-Detection Modalities |
| Figure 4 – Global HLS Bio-Detection Systems, Service & Upgrade Market Forecast [$ Million] – 2010-2014 |
| Figure 5 – Global HLS Bio-Detection Systems & Service Market Share [%] – 2008, 2011 & 2014 |
| Figure 6 – Global Bio-Detection (Systems, Service & Upgrade) Market Forecast [$ Million] by Countries & Regions – 2008-2014 |
| Figure 7 – Global HLS Bio-Detection (Systems, Service & Upgrade) Markets Forecast by Modality [$ Million] – 2010-2014 |
| Figure 8 – Global HLS Bio-Detection Systems , Service & Upgrade Market Forecast by Modality Share [%] – 2008, 2011 & 2014 |
| Figure 9 – Global Bio-Detection Systems Market by Generation [$ Million] – 2008-2014 |
| Figure 10 – Bio-Detection Systems Market by Generation [%] – 2008, 2011 & 2014 |
| Figure 11 – Bio-Detection Service Business Forecast by Technology Generation [$ Million] – 2008-2014 |
| Figure 12 – Bio-Detection Service and Upgrade Business Forecast by Technology Generation Share [%] – 2008, 2011 & 2014 |
| Figure 13 – Bio-Detection Industry Competitive Analysis |
| Figure 14 – Bio-Detection Industry SWOT Analysis |
| Figure 15 – Airborne Bacterial Concentration Fluctuation in a Single Day |
| Figure 16 – Cross-Section of Cascade Impactor: PIXE International Corporation |
| Figure 17 – TSI’s Model 3317 System with Concentrator, GPS Receiver & Wireless Data Radio |
| Figure 18 – Comparison in Weight of Pathogens Between BW Agents and CW Agents [mg] |
| Figure 19 – Typical Point Detection Automated Architecture (With a Combined Trigger/Cue) |
| Figure 20 – Biological Detection Technologies – 2010-2014 |
| Figure 21 – Flow Cytometry |
| Figure 22 – Gas Chromatography |
| Figure 23 – Polymerase Chain Reaction |
| Figure 24 – RT–PCR |
| Figure 25 – Principles of Real-Time PCR |
| Figure 26 – DNA Micro-arrays – Principles of Operation |
| Figure 27 – Schematic for Antibody Protein |
| Figure 28 – Hand Held Detectors: Alexeter Guardian Reader System and Tetracore Test Strips |
| Figure 29 – Roche Applied Science – Light CyclerTM Model 1.2 |
| Figure 30 – Global Market by Systems, Upgrade & Service Segments – 2008-2014 |
| Figure 31 – Global HLS Bio-Detection Systems & Service Market Share [%] – 2009 & 2014 |
| Figure 32 – Global Bio-Detection (Systems, Service & Upgrade) Market Forecast [$ Million] by Countries & Regions – 2008-2014 |
| Figure 33 – Global Bio-Detection (Systems, Service & Upgrade) Market Share [%] by Countries & Regions – 2009 & 2014 |
| Figure 34 – Global Bio-Detection Systems Market by Generation [$ Million] – 2010-2014 |
| Figure 35 – Global Bio-Detection Systems Market by Generation [%] – 2009 & 2014 |
| Figure 36 – Global Systems Market [$ Million] by Indoor, Outdoor, Hand-Held and Mobile Labs Segments – 2008-2014 |
| Figure 37 – Global Systems Market Share [%] by Indoor, Outdoor, Hand-Held and Mobile Labs Segments – 2009 & 2014 |
| Figure 38 – Global Service & Upgrade Business by Generation [$ Million] – 2008-2014 |
| Figure 39 – Global Bio-Detection Service and Upgrade Business by Generation Share [%] – 2009 & 2014 |
| Figure 40 – Global Service & Upgrade Market by Indoor, Outdoor, Hand-Held and Mobile Labs Segments – 2008-2014 |
| Figure 41 – Global Service & Upgrade Market Share [%] by Indoor, Outdoor, Hand-Held and Mobile Labs Segments – 2009 & 2014 |
| Figure 42 – US Cumulative 2001-2009 HLS-HLD Bio-Defense Funding [$Million], by Agency |
| Figure 43 – Bio-Defense Funding Share [%], by Agency – 2001 & 2009 |
| Figure 44 – US Bio-Detection Systems Market by Generation [$ Million] – 2008-2014 |
| Figure 45 – US Bio-Detection Systems Market by Generation Share [%] – 2009 & 2014 |
| Figure 46 – US Bio-Detection Systems Market by Modality [$ Million] – 2008-2014 |
| Figure 47 – US Bio-Detection Systems Market by Modality Share [%] – 2009 & 2014 |
| Figure 48 – US Outdoor Systems Standoff Detectors Market by Generation [$ Million] – 2008-2014 |
| Figure 49 – US Outdoor Standoff Detectors Systems Market by Generation Share [%] – 2009 & 2014 |
| Figure 50 – US Indoor Standoff Detectors Systems Market by Generation [$ Million] – 2008-2014 |
| Figure 51 – US Indoor Standoff Detectors Systems Market by Generation Share [%] – 2009 & 2014 |
| Figure 52 – US Hand-Held Systems Market [$ Million] by Generation – 2008-2014 |
| Figure 53 – US Hand-Held Systems Market Share [%] by Generation – 2009 & 2014 |
| Figure 54 – US Mobile Labs Market by Generation [$ Million] – 2008-2014 |
| Figure 55 – US Mobile Labs Market by Generation Share [%] – 2009 & 2014 |
| Figure 56 – US Bio-Detection Service & Upgrade Business Forecast by Modality [$ Million] – 2008-2014 |
| Figure 57 – US Bio-Detection Service & Upgrade Business Forecast by Modality Share [%] – 2009 & 2014 |
| Figure 58 – US Service & Upgrade Business Forecast by Generation [$ Million] – 2008-2014 |
| Figure 59 – US Service & Upgrade Business by Generation [%] – 2009 & 2014 |
| Figure 60 – The EU Counter-Terrorism Strategy |
| Figure 61 – Member States Primary Responsibility |
| Figure 62 – Credit Card-sized Portable Lab (lab-on-a-chip) For Ultra High Speed PCR |
| Figure 63 – UK, Germany, France, Italy and Spain Bio-Detection Systems Market by Generation [$ Million] – 2008-2014 |
| Figure 64 – UK, Germany, France, Italy and Spain Bio-Detection Systems Market by Generation Share [%] – 2009 & 2014 |
| Figure 65 – UK, Germany, France, Italy and Spain Bio-Detection Systems Market by Modality [$ Million] – 2008-2014 |
| Figure 66 – UK, Germany, France, Italy and Spain Bio-Detection Systems Market by Modality Share [%] – 2009 & 2014 |
| Figure 67 – UK, Germany, France, Italy and Spain Outdoor Detectors Market by Generation [$ Million] – 2008-2014 |
| Figure 68 – UK, Germany, France, Italy and Spain Outdoor Detectors Systems Market by Generation Share [%] – 2009 & 2014 |
| Figure 69 – UK, Germany, France, Italy and Spain Indoor Detectors Market by Generation [$ Million] – 2008-2014 |
| Figure 70 – UK, Germany, France, Italy and Spain Indoor Detectors Market by Generation Share [%] – 2009 & 2014 |
| Figure 71 – UK, Germany, France, Italy and Spain Hand-Held Detection Systems Market [$ Million] by Generation – 2008-2014 |
| Figure 72 – UK, Germany, France, Italy and Spain Hand-Held Systems Market Share [%] by Generation – 2009 & 2014 |
| Figure 73 – UK, Germany, France, Italy and Spain Mobile Labs Market by Generation [$ Million] – 2008-2014 |
| Figure 74 – UK, Germany, France, Italy and Spain Mobile Labs Market by Generation Share [%] – 2009 & 2014 |
| Figure 75 – UK, Germany, France, Italy and Spain Bio-Detection Service & Upgrade Business Forecast by Modality [$ Million] – 2008-2014 |
| Figure 76 – UK, Germany, France, Italy and Spain Bio-Detection Service & Upgrade Business Forecast by Modality Share [%] – 2009 & 2014 |
| Figure 77 – UK, Germany, France, Italy and Spain Bio-Detection Service & Upgrade Business Forecast by Generation [$ Million] – 2008-2014 |
| Figure 78 – UK, Germany, France, Italy and Spain Service & Upgrade Business by Generation [%] – 2009 & 2014 |
| Figure 79 – A Bio-attack Decontamination Drill In Japan |
| Figure 80 – China, Taiwan, Japan, India and Middle East Bio-Detection Systems Market by Generation [$ Million] – 2008-2014 |
| Figure 81 – China, Taiwan, Japan, India and Middle East Bio-Detection Systems Market by Generation Share [%] – 2009 & 2014 |
| Figure 82 – China, Taiwan, Japan, India and Middle East Bio-Detection Systems Market by Modality [$ Million] – 2008-2014 |
| Figure 83 – China, Taiwan, Japan, India and Middle East Bio-Detection Systems Market by Modality Share [%] – 2009 & 2014 |
| Figure 84 – China, Taiwan, Japan, India and Middle East Outdoor Detectors Market by Generation [$ Million] – 2008-2014 |
| Figure 85 – China, Taiwan, Japan, India and Middle East Outdoor Detectors Systems Market by Generation Share [%] – 2009 & 2014 |
| Figure 86 – China, Taiwan, Japan, India and Middle East Indoor Detectors Market by Generation [$ Million] – 2008-2014 |
| Figure 87 – China, Taiwan, Japan, India and Middle East Indoor Standoff Detectors Market by Generation Share [%] – 2009 & 2014 |
| Figure 88 – China, Taiwan, Japan, India and Middle East 1st Responder Hand-Held Detection Systems Market [$ Million] by Generation – 2008-2014 |
| Figure 89 – China, Taiwan, Japan, India and Middle East Hand-Held Systems Market Share [%] by Generation – 2009 & 2014 |
| Figure 90 – China, Taiwan, Japan, India and Middle East Mobile Labs Market by Generation [$ Million] – 2008-2014 |
| Figure 91 – China, Taiwan, Japan, India and Middle East Mobile Labs Market by Generation Share [%] – 2009 & 2014 |
| Figure 92 – China, Taiwan, Japan, India and Middle East Bio-Detection Service & Upgrade Business by Modality [$ Million] – 2008-2014 |
| Figure 93 – China, Taiwan, Japan, India and Middle East Bio-Detection Service & Upgrade Business by Modality Share [%] – 2009 & 2014 |
| Figure 94 – China, Taiwan, Japan, India and Middle East Service & Upgrade Business by Generation [$ Million] – 2008-2014 |
| Figure 95 – China, Taiwan, Japan, India and Middle East Service & Upgrade Business by Generation [%] – 2009 & 2014 |
| Figure 96 – ROW Bio-Detection Systems Market by Generation [$ Million] – 2008-2014 |
| Figure 97 – ROW Bio-Detection Systems Market by Generation Share [%] – 2009 & 2014 |
| Figure 98 – ROW Bio-Detection Systems Market by Modality [$ Million] – 2008-2014 |
| Figure 99 – ROW Bio-Detection Systems Market by Modality Share [%] – 2009 & 2014 |
| Figure 100 – ROW Outdoor Detectors Market by Generation [$ Million] – 2008-2014 |
| Figure 101 – ROW Outdoor Detectors Market by Generation Share [%] – 2009 & 2014 |
| Figure 102 – Indoor Detectors Market by Generation [$ Million] – 2008-2014 |
| Figure 103 – ROW Indoor Detectors Market by Generation Share [%] – 2009 & 2014 |
| Figure 104 – ROW Hand-Held Systems Market [$ Million] by Generation – 2008-2014 |
| Figure 105 – ROW Hand-Held Systems Market Share [%] by Generation – 2009 & 2014 |
| Figure 106 – ROW Mobile Labs Market by Generation [$ Million] – 2008-2014 |
| Figure 107 – ROW First Responder Mobile Labs Market by Generation Share [%] – 2009 & 2014 |
| Figure 108 – ROW Bio-Detection Service & Upgrade Business by Modality [$ Million] – 2008-2014 |
| Figure 109 – ROW Bio-Detection Service & Upgrade Business Forecast by Modality Share [%] – 2009 & 2014 |
| Figure 110 – ROW Bio-Detection Service & Upgrade Business Forecast by Generation [$ Million] – 2008-2014 |
| Figure 111 – ROW Bio-Detection Service & Upgrade Business Forecast by Generation [%] – 2009 & 2014 |
| Figure 112 – Factors Affecting Biological Detection Deployment and Technologies – 2010-2014 |
| Figure 113 – Past Bio-Detection Timeline |
| Figure 114 – Civilians in China During the SARS Epidemic |
| Figure 115 – A Typical Microfluidic Device |
| Figure 116 – Bio-Defense R&D Federal Funding by Agency [$ Million] – 2010-2014 |
| Figure 117 – DHS Bio-Security R&D Budget Forecast [$ Million] – 2010-2014 |
| Figure 118 – DOD Bio-security R&D Budget Forecast [$ Million] – 2010-2014 |
| Figure 119 – DHHS Bio-security R&D Budget Forecast [$ Million] – 2010-2014 |
| Figure 120 – Other Agencies Bio-Security R&D Budget Forecast [$ Million] – 2010-2014 |
| Figure 121 – BAS101 Scheme. |
| Figure 122 – Categories of the Bio-threat Divides |
| Figure 123 – The Spraying of Anthrax from Aum Shinrikyo’s Headquarters June 1993 |
| Figure 124 – Anthrax Spores and Disease |
| Figure 125 – Cholera Bacteria |
| Figure 126 – Pneumonic Plague – The Disease |
| Figure 127 – Tularemia – The Disease |
| Figure 128 – Smallpox Virus And Disease |
| Figure 129 – Ebola Virus – Electron Microscopy Image |
| Figure 130 – VEE – Venezuelan Equine Encephalitis Virus in the Olfactory Mucosa of a Mouse |
| Figure 131 – Q Fever |
| Figure 132 – Typhus Microbe – Electron Microscopy Image |
| Figure 133 – Castor Plant And Structure For The Ricin Toxin |
| Figure 134 – The Dinoflagellate Alexandrium Tamarense And Structure of Saxitoxin |
List of Tables
| Table 1 – US Federal HLS-HLD Bio-Defense Funding [$Million] – 2001-2009 |
| Table 2 – Global HLS Bio-Detection Systems, Service & Upgrade Market Forecast [$ Million] – 2008-2014 |
| Table 3 – Global HLS Bio-Detection Systems, Service & Upgrade Market Forecast by Expenditure Share [%] – 2010-2014 |
| Table 4 – Global HLS Bio-Detection (Systems, Service & Upgrade) Market Forecast [$ Million] by Countries & Regions – 2008-2014 |
| Table 5 – Global HLS Bio-Detection Systems, Service & Upgrade Market Forecast by Modality [$ Million] – 2008-2014 |
| Table 6 – Global HLS Bio-Detection Systems , Service & Upgrade Market Forecast by Modality Share [%] – 2008-2014 |
| Table 7 – Bio-Detection Systems Market by Generation [$ Million] – 2008-2014 |
| Table 8 – Bio-Detection Systems Market by Generation [%] – 2008-2014 |
| Table 9 – Bio-Detection Service and Upgrade Business Forecast by Technology Generation [$ Million] – 2008-2014 |
| Table 10 – Bio-Detection Service and Upgrade Business Forecast by Technology Generation Share [%] – 2008-2014 |
| Table 11 – Bio Surveillance, Detection & Bio-forensics Challenges – 2010-2014 |
| Table 12 – 40 Countries’ Bio-Defense & Bio-Detection Technologies Performance Rating |
| Table 13 – Cost, Speed & Accuracy Comparison of Bio-Detection Technologies |
| Table 14 – Global Market by Systems, Upgrade and Service Segments [$Million] – 2008-2014 |
| Table 15 – Global HLS Bio-Detection Systems , Service & Upgrade Market Forecast by Expenditure Share [%] – 2010-2014 |
| Table 16 – Global HLS Bio-Detection (Systems, Service & Upgrade) Market Forecast [$ Million] by Countries & Regions – 2008-2014 |
| Table 17 – Global HLS Bio-Detection (Systems, Service & Upgrade) Market Share [%] by Countries & Regions – 2009-2014 |
| Table 18 – Global Bio-Detection Systems Market by Generation [$ Million] – 2010-2014 |
| Table 19 – Global Bio-Detection Systems Market by Generation [%] – 2010-2014 |
| Table 20 – Global Systems Market by Indoor, Outdoor, Hand-Held and Mobile Labs Segments – 2008-2014 |
| Table 21 – Global Systems Market Share [%] by Indoor, Outdoor, Hand-Held and Mobile Labs Segments – 2008-2014 |
| Table 22 – Global Bio-Detection Service and Upgrade Business by Generation [$ Million] – 2008-2014 |
| Table 23 – Global Bio-Detection Service and Upgrade Business Forecast by Generation Share [%] – 2008-2014 |
| Table 24 – Global Service & Upgrade Market by Indoor, Outdoor, Hand-Held and Mobile Labs Segments – 2008-2014 |
| Table 25 – Global Service & Upgrade Market Share [%] by Indoor, Outdoor, Hand-Held and Mobile Labs Segments – 2009 & 2014 |
| Table 26 – The CDC Biological Threat Agents Categorization |
| Table 27 – US Federal HLS-HLD Bio-Defense Funding [$ Millions], by Agency – FY2001-FY2009 |
| Table 28 – US Bio-Detection Systems Market by Generation [$ Million] – 2008-2014 |
| Table 29 – US Bio-Detection Systems Market by Generation Share [%] – 2008-2014 |
| Table 30 – US Bio-Detection Market by Modality [$ Million] – 2008-2014 |
| Table 31 – US Bio-Detection Systems Market by Modality Share [%] – 2008-2014 |
| Table 32 – US Outdoor Standoff Detectors Systems Market by Generation [$ Million] – 2008-2014 |
| Table 33 – US Outdoor Standoff Detectors Systems Market by Generation Share [%] – 2008-2014 |
| Table 34 – US Indoor Detectors Systems Market by Generation [$ Million] – 2008-2014 |
| Table 35 – US Indoor Standoff Detectors Systems Market by Technological Generation Share [%] – 2008-2014 |
| Table 36 – US Hand-Held Systems Market [$ Million] by Generation – 2008-2014 |
| Table 37 – US Hand-Held Systems Market Share [%]by Generation – 2008-2014 |
| Table 38 – US Mobile Labs Market by Technology Generation [$ Million] – 2008-2014 |
| Table 39 – US Mobile Labs Market Share [%] by Generation – 2008-2014 |
| Table 40 – US Service & Upgrade Business by Modality [$ Million] – 2008-2014 |
| Table 41 – US Bio-Detection Service & Upgrade Business by Modality Share [%] – 2008-2014 |
| Table 42 – US Service Business Forecast by Generation [$ Million] – 2008-2014 |
| Table 43 – US Service Business by Generation Share [%] – 2008-2014 |
| Table 44 – UK, Germany, France, Italy and Spain Bio-Detection Systems Market by Generation [$ Million] – 2008-2014 |
| Table 45 – UK, Germany, France, Italy and Spain Bio-Detection Systems Market Share by Generation [%] – 2008-2014 |
| Table 46 – UK, Germany, France, Italy and Spain Bio-Detection Market by Modality [$ Million] – 2008-2014 |
| Table 47 – UK, Germany, France, Italy and Spain Bio-Detection Systems Market by Modality Share [%] – 2008-2014 |
| Table 48 – UK, Germany, France, Italy and Spain Outdoor Detectors Market by Technology Generation [$ Million] – 2008-2014 |
| Table 49 – UK, Germany, France, Italy and Spain Outdoor Detectors Market by Technology Generation Share [%] – 2008-2014 |
| Table 50 – UK, Germany, France, Italy and Spain Indoor Standoff Detectors Market by Technology Generation [$ Million] – 2008-2014 |
| Table 51 – UK, Germany, France, Italy and Spain Indoor Detectors Market by Generation Share [%] – 2008-2014 |
| Table 52 – UK, Germany, France, Italy and Spain Hand-Held Systems Market [$ Million] by Generation – 2008-2014 |
| Table 53 – UK, Germany, France, Italy and Spain Hand-Held Detection Systems Market Share by Generation [%] – 2008-2014 |
| Table 54 – UK, Germany, France, Italy and Spain Mobile Labs Market by Generation [$ Million] – 2008-2014 |
| Table 55 – UK, Germany, France, Italy and Spain Mobile Labs Market Share [%] by Generation – 2008-2014 |
| Table 56 – UK, Germany, France, Italy and Spain Service & Upgrade Business by Modality [$ Million] – 2008-2014 |
| Table 57 – UK, Germany, France, Italy and Spain Bio-Detection Service & Upgrade Business Forecast by Modality Share [%] – 2008-2014 |
| Table 58 – UK, Germany, France, Italy and Spain Service Business by Generation [$ Million] – 2008-2014 |
| Table 59 – UK, Germany, France, Italy and Spain Service Business Forecast by Generation Share [%] – 2008-2014 |
| Table 60 – China, Taiwan, Japan, India and Middle East Bio-Detection Systems Market by Generation [$ Million] – 2008-2014 |
| Table 61 – China, Taiwan, Japan, India and Middle East Bio-Detection Systems Market by Generation Share [%] – 2008-2014 |
| Table 62 – China, Taiwan, Japan, India and Middle East Bio-Detection Market by Modality [$ Million] – 2008-2014 |
| Table 63 – China, Taiwan, Japan, India and Middle East Bio-Detection Systems Market by Modality Share [%] – 2008-2014 |
| Table 64 – China, Taiwan, Japan, India and Middle East Outdoor Detectors Market by Generation [$ Million] – 2008-2014 |
| Table 65 – China, Taiwan, Japan, India and Middle East Outdoor Detectors Market by Generation Share [%] – 2008-2014 |
| Table 66 – China, Taiwan, Japan, India and Middle East Indoor Detectors Market by Generation [$ Million] – 2008-2014 |
| Table 67 – China, Taiwan, Japan, India and Middle East Indoor Detectors Market by Generation Share [%] – 2008-2014 |
| Table 68 – China, Taiwan, Japan, India and Middle East Hand-Held Detection Systems Market [$ Million] by Generation – 2008-2014 |
| Table 69 – China, Taiwan, Japan, India and Middle East 1st Responder Hand-Held Detection Systems Market by Generation Share [%] – 2008-2014 |
| Table 70 – China, Taiwan, Japan, India and Middle East Mobile Labs Market by Generation [$ Million] – 2008-2014 |
| Table 71 – China, Taiwan, Japan, India and Middle East Mobile Labs Market by Generation Share [%] – 2008-2014 |
| Table 72 – China, Taiwan, Japan, India and Middle East Bio-Detection Service & Upgrade Business by Modality [$ Million] – 2008-2014 |
| Table 73 – China, Taiwan, Japan, India and Middle East Bio-Detection Service & Upgrade Business by Modality Share [%] – 2008-2014 |
| Table 74 – China, Taiwan, Japan, India and Middle East Service Business by Generation [$ Million] – 2008-2014 |
| Table 75 – China, Taiwan, Japan, India and Middle East Bio-Detection Service Business by Generation Share [%] – 2008-2014 |
| Table 76 – ROW Bio-Detection Systems Market by Generation [$ Million] – 2008-2014 |
| Table 77 – ROW Bio-Detection Systems Market by Generation Share [%] – 2008-2014 |
| Table 78 – ROW Bio-Detection Market by Modality [$ Million] – 2008-2014 |
| Table 79 – ROW Bio-Detection Systems Market by Modality Share [%] – 2008-2014 |
| Table 80 – ROW Outdoor Detectors Market by Generation [$ Million] – 2008-2014 |
| Table 81 – ROW Outdoor Detectors Market by Generation Share [%] – 2008-2014 |
| Table 82 – ROW Indoor Detectors Market by Generation [$ Million] – 2008-2014 |
| Table 83 – ROW Indoor Detectors Market by Generation Share [%] – 2008-2014 |
| Table 84 – ROW Hand-Held Systems Market [$ Million] by Generation – 2008-2014 |
| Table 85 – ROW Hand-Held Systems Market Share [%] by Generation – 2008-2014 |
| Table 86 – ROW Mobile Labs Market by Generation [$ Million] – 2008-2014 |
| Table 87 – ROW First Responders Market Share [%] by Generation –2008-2014 |
| Table 88 – ROW Bio-Detection Service & Upgrade Business Forecast by Modality [$ Million] – 2008-2014 |
| Table 89 – ROW Bio-Detection Service & Upgrade Business by Modality Share [%] – 2008-2014 |
| Table 90 – ROW Service Business by Generation [$ Million] – 2008-2014 |
| Table 91 – ROW Bio-Detection Service Business Forecast by Technology Generation Share [%] – 2008-2014 |
| Table 92 – US Bio-Defense R&D Federal Funding by Agency [$ Million] – 2010-2014 |
| Table 93 – Prices of Bio-Detection Equipment |
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