U.S. Bio-Detection Homeland Security & Defense Technology & Market Forecast – 2010-2014
| February 2009 |
Publication: Q1 2009, Pages: 222 , Figures: 89, Tables: 57

The bio-detection markets present some of the fastest growing and vibrant markets in the homeland security industry. The Obama administration is committed to accelerating the pace of bio-terror mitigation spending. In February 2009, the Congress passed a bill that included more than $1.7 billion in additional funding for bio-security and bio-health, and R&D.
This report describes the technologies and markets dedicated to using biological detectors for either constant, automatic, standoff surveillance of an indoor facility (e.g., mall, postal distribution center), an outdoor environment, or manual usage by 1st responders to check whether or not suspect traces consist of bio-terror agents. Such systems, in the context of homeland security, are mainly designed to mitigate the effects of biological terrorism.
HSRC’s team of scientists and industry executives meticulously researched and analyzed each of the 4 modalities of bio-detection:
- Outdoor Automatic Standoff-Detectors (e.g., Project BioWatch)
- Indoor Automatic Standoff-Detectors
- Emergency Responder Biological Mobile Labs
- Emergency Responder Biological Hand-Held Detectors
For each modality, the research provides a detailed analysis and forecast for three generations of technologies, providing a look at the twelve market segments that will make up this industry for the next five years.
For each of the modalities, the research provides the following:
- Present & Next Generation Technologies – present technologies analysis and an in depth analysis of bio-detection candidates of next generation technologies
- Current and upcoming business opportunities –18 specific business opportunities outlined and analyzed
- 2010-2014 Market Forecasts– various and detailed forecasts of annual sales in units and dollars, for the next fice years
- 2010-2014 Service and Upgrade Business – five year forecasts of the service and equipment installation and upgrade business, which are the main source of gross margin for this industry
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| 1. Scope | 24 |
| 1.1. Definition of Biological Terrorism | 24 |
| 1.2. Scope | 25 |
| 1.2.1. Bio Weapon Types | 26 |
| 1.3. Basic Assumptions | 27 |
| 1.3.1. General | 27 |
| 1.3.2. Why Conduct Constant Surveillance for Biological Warfare Threats? | 27 |
| 1.3.3. Possible Scenario Analysis | 28 |
| 1.4. Methodology | 28 |
| 1.4.1. Research Methods | 28 |
| 1.4.2. Report Structure | 28 |
| 1.5. Who is This Report For? | 29 |
| 2. Executive Summary | 30 |
| 2.1. Main Conclusions | 30 |
| 2.2. The Threat of Bioterrorism | 33 |
| 2.3. How Real Is The Bioterrorism Threat? | 33 |
| 2.4. Defending Against Bioterrorism | 34 |
| 2.4.1. Project BioWatch | 37 |
| 2.4.2. Project BioSense | 38 |
| 2.4.3. Project BioShield | 39 |
| 2.5. Bio-Detection – The Industry | 39 |
| 2.6. Bio-Detection Market Forecast – 2010-2014 | 40 |
| 2.6.1. Total Bio-Detection Systems and Service Market Forecast – 2010-2014 | 40 |
| 2.6.2. Bio-Detection Systems & Service Market Forecast by Modality – 2010-2014 | 42 |
| 2.6.3. Bio-Detection Market Forecast by Technology Generation – 2010-2014 | 44 |
| 2.7. Bio-Detection – Next Generation Business Opportunities | 47 |
| 2.8. Bio-Detection – Technologies Outlook | 47 |
| 3. Bio-Detection Market – Drivers | 48 |
| 4. Bio-Detection Market – Inhibitors | 49 |
| 5. The Obama Administration Bio Terror Mitigation Strategy | 50 |
| 5.1. Bio-Defense Funding | 50 |
| 5.1.1. DHHS Bio-Defense Missions and Funding | 53 |
| 5.1.2. DHS Bio-Defense Missions and Funding | 53 |
| 5.1.3. DOD Bio-Defense Missions and Funding | 54 |
| 5.1.4. DOA Bio-Defense Missions and Funding | 54 |
| 5.1.5. EPA Bio-Defense Missions and Funding | 55 |
| 5.1.6. Other Bio-Defense Missions and Funding | 55 |
| 5.2. The Obama Administration Bio-Defense Strategy | 55 |
| 6. Bio-Detection – Technologies Overview | 57 |
| 6.1. Bio-Detection Technology Challenges | 57 |
| 6.1.1. Sampling the Environment | 58 |
| 6.2. The Bio-Detection Process | 59 |
| 6.2.1. Bio-Detectors in a Multitude of Ambient Settings | 59 |
| 6.2.2. Bio-Detection Triggering | 60 |
| 6.2.3. Collection of Particles | 60 |
| 6.2.4. Bio-Particle Detectors | 61 |
| 6.2.5. Bio-Agent Identification | 62 |
| 7. Bio-Detection Technological Challenges | 63 |
| 7.1. Challenge 1 – Detection of Small Particle Concentration | 63 |
| 7.2. Challenge 2 – Eliminating Bio Background | 63 |
| 7.3. Challenge 3 – Expensive Reagents | 64 |
| 7.4. Challenge 4 – Expensive Equipment Maintenance | 64 |
| 7.5. Challenge 5 – Adapting Equipment to Changing Environments | 64 |
| 7.6. Challenge 6 – Dealing With Emerging Threats | 65 |
| 8. Bio Detection Technologies Review & Outlook – 2010-2014 | 66 |
| 8.1. Bio-Detection – Core Technologies Comparison | 66 |
| 8.2. Collector/Concentrator Core Technologies | 69 |
| 8.3. Cyclone Collectors | 69 |
| 8.4. Variable Particle-Size Impactor | 70 |
| 8.5. Virtual Impactors | 70 |
| 8.6. Impingers | 71 |
| 8.7. Reagentless Trigger Core Technologies | 71 |
| 8.7.1. Flow Cytometry | 72 |
| 8.7.2. Particle Sizing | 73 |
| 8.7.3. Gas Chromatography | 74 |
| 8.7.4. Trigger Technologies – Drivers | 74 |
| 8.7.5. Trigger Technologies – Inhibitors | 75 |
| 8.8. DNA Based Diagnostic Core Technologies | 75 |
| 8.8.1. Overview of DNA-Based Detection | 75 |
| 8.8.2. Polymerase Chain Reaction (PCR) | 76 |
| 8.8.3. DNA / RNA Microarrays | 80 |
| 8.8.4. DNA Technology Drivers | 82 |
| 8.8.5. DNA Technology Inhibitors | 82 |
| 8.9. Antibody-Antigen Diagnostic Core Technologies | 83 |
| 8.9.1. Overview of Antibody-Antigen Reaction | 83 |
| 8.9.2. Hand-Held Immuno-Chromatographic Assays (HHA) | 84 |
| 8.9.3. Magnetic Microbead-Base Assays | 84 |
| 8.9.4. Microfluidic Devices – “Lab on a Chip” | 85 |
| 8.9.5. Fluorescence Imaging | 85 |
| 8.9.6. Electrochemical-Luminescence (ECL) | 85 |
| 8.9.7. Antibody/Antigen Technology – Drivers | 86 |
| 8.9.8. Antibody/Antigen Technology – Inhibitors | 86 |
| 8.1. Signal Analysis Algorithms | 86 |
| 8.10.1. Clustering / Classifier Algorithms | 86 |
| 8.10.2. Image Analysis Algorithms | 87 |
| 8.10.3. Decision Algorithms | 87 |
| 8.10.4. Algorithm Drivers | 87 |
| 8.10.5. Algorithm Inhibitors | 87 |
| 8.11. Rapid Microbiological Technologies | 88 |
| 9. Biological Detection – Overview by Application | 89 |
| 9.1.1. Application 1 – Emergency Responder Hand-Held Detectors | 89 |
| 9.1.2. Application 2 – Emergency Responder Mobile Labs | 90 |
| 9.1.3. Application 3 – Indoor Standoff Detectors | 91 |
| 9.1.4. Application 4 – Outdoor Standoff Detectors | 92 |
| 10. U.S. Bio-Detection Systems Market Outlook – 2010-2014 | 93 |
| 10.1. Scope, Assumptions and Overview | 93 |
| 10.1.1. Scope | 93 |
| 10.2. Bio-Detection Systems Revenue Sales Forecast – 2010-2014 | 94 |
| 10.2.1. Bio-Detection Systems Revenue Sales by Generation Forecast – 2010-2014 | 94 |
| 10.2.2. Bio-Detection Systems Sales by Modality Forecast – 2010-2014 | 96 |
| 10.3. Bio-Detection Systems Quantity Sales Forecast – 2010-2014 | 98 |
| 10.3.1. Bio-Detection Systems Quantity Sales by Generation Forecast – 2010-2014 | 98 |
| 10.3.2. Bio-Detection Systems Quantity Sales by Modality Forecast – 2010-2014 | 100 |
| 10.4. Bio-Detection Systems Installed Base Forecast – 2010-2014 | 102 |
| 10.4.1. Bio-Detection Systems Installed Base by Generation Forecast – 2010-2014 | 102 |
| 10.4.2. Bio-Detection Systems Installed Base by Modality Forecast – 2010-2014 | 104 |
| 10.5. Bio-Detection Outdoor Standoff-Detection Systems – Market Forecast – 2010-2014 | 106 |
| 10.5.1. Outdoor Standoff Detection Systems Revenue Sales Outlook – 2010-2014 | 106 |
| 10.5.2. Outdoor Standoff Detection Systems Quantity Sales Outlook – 2010-2014 | 108 |
| 10.5.3. Outdoor Standoff Detection Systems Installed Base Outlook – 2010-2014 | 110 |
| 10.6. Bio-Detection Indoor Systems Standoff-Detection Market Forecast – 2010-2014 | 112 |
| 10.6.1. Indoor Standoff Systems Detection Sales Outlook – 2010-2014 | 113 |
| 10.6.2. Indoor Standoff Detection Systems Unit Sales Outlook – 2010-2014 | 115 |
| 10.6.3. Indoor Standoff Detection Systems Installed Base – 2010-2014 | 117 |
| 10.7. Bio-Detection – Point-Detection (Detect-to-Treat) Systems – Installed Base Forecast – 2010-2014 | 119 |
| 10.7.1. Point-Detection Summary Overview | 119 |
| 10.8. Bio-Detection First Responder Hand-Held Detection Systems Market Forecast – 2010-2014 | 120 |
| 10.8.1. First Responder Hand-Held Detection Systems Sales Outlook – 2010-2014 | 120 |
| 10.8.2. First Responder Hand-Held Detection Systems Quantity Sales Outlook – 2010-2014 | 122 |
| 10.8.3. First Responder Hand-Held Detection Systems Installed Base – 2010-2014 | 124 |
| 10.9. Bio-Detection First Responder Mobile Labs Detection Systems Market Forecast – 2010-2014 | 126 |
| 10.9.1. First Responder Mobile Labs Sales Outlook – 2010-2014 | 126 |
| 10.9.2. First Responder Mobile Labs Quantity Sales Outlook – 2010-2014 | 128 |
| 10.9.3. First Responder Mobile Labs Installed Base – 2010-2014 | 130 |
| 11. Bio-Detection Service Business Outlook – 2010-2014 | 133 |
| 11.1. Bio-Detection Service & Upgrade Business Forecast by Modality – 2010-2014 | 133 |
| 11.2. Bio-Detection Service Business Forecast by Technology Generation – 2010-2014 | 135 |
| 12. Bio-Detection Business Opportunities – 2010-2014 | 138 |
| 12.1. Historical Perspective: A Market Waiting for Transition | 138 |
| 12.1.1. The Current and Future HLS Bio-Defense Strategy for Detection | 138 |
| 12.1.2. Factors Affecting Biological Detectors Deployment and Technologies – 2010-2014 | 139 |
| 12.1.3. Biological Detection Technology Timeline – 1992-2014 | 141 |
| 12.2. Business Opportunities for Next Generation HLS Bio-Detection Systems | 143 |
| 12.2.1. Business Opportunity 1 – Emerging Threats | 143 |
| 12.2.2. Business Opportunity 2 – Human Sentinel Surveillance System | 144 |
| 12.2.3. Business Opportunity 3 – Animal Sentinel Surveillance System | 145 |
| 12.2.4. Business Opportunity 4 – Biological IC3 – Biological Threat Assessment Intelligence Command, Control, and Communication Infrastructure | 145 |
| 12.2.5. Business Opportunity 5 – Reducing False Alarms – Lesser False Positives and False Negatives | 145 |
| 12.2.6. Business Opportunity 6 – Reducing Cost – Minimizing Use of Non-Reusable Reagents | 146 |
| 12.3. Outdoor Standoff Biological Detectors | 146 |
| 12.3.1. Business Opportunity 7 – Bioagent Autonomous Networked Detectors (BAND) | 147 |
| 12.3.2. Business Opportunity 8 – Rapid Automated Biological Identification System (RABIS) | 147 |
| 12.3.3. Business Opportunity 9 – First Responder Portable Hand-Held Detector | 148 |
| 12.3.4. Business Opportunity 10 – First Responder Mobile Biological Detection Station | 149 |
| 12.3.5. Business Opportunity 11 – Regional Automatic Detector – Outdoor Standoff Detectors | 149 |
| 12.3.6. Business Opportunity 12 – Networked Automatic Detector – Indoor Standoff Detectors | 150 |
| 12.3.7. Business Opportunity 13 – External Spread of Bioagent Detection | 151 |
| 12.3.8. Business Opportunity 14 – Internal Spread of Bioagent | 151 |
| 12.4. Other Bio-Detection Technologies – Business Opportunities | 152 |
| 12.4.1. Business Opportunity 15 – “Lab on a Chip” – Miniature Detection Devices | 152 |
| 12.4.2. Business Opportunity 16 – Reagentless Specific Detection Assays | 153 |
| 12.4.3. Business Opportunity 17 – Laser Induced Breakdown Spectroscopy (LIBS) | 154 |
| 12.4.4. Business Opportunity 18 – Raman Spectroscopy-based Reagentless Detection | 154 |
| 12.5. Future Technologies and Systems | 154 |
| 13. Bio-Defense Federal R&D Funding Opportunities – 2010-2014 | 156 |
| 13.1. Summary & Outlook | 156 |
| 13.2. Bio-Defense Federal R&D Funding Forecast – 2010-2014 | 156 |
| 13.2.1. DHS Biosecurity R&D | 157 |
| 13.2.2. DOD Bio-Security R&D | 159 |
| 13.2.3. DHHS Biosecurity R&D | 160 |
| 13.2.4. Other Agencies Biosecurity R&D | 161 |
| 13.3. HLS-HLD Bio-Detection R&D Funding – Drivers | 162 |
| 13.4. HLS-HLD Bio-Detection R&D Funding Opportunities – Inhibitors | 163 |
| 13.5. DHS – Biological Detection HLS Technologies R&D Programs | 163 |
| 13.5.1. Surveillance and Detection R&D | 163 |
| 13.5.2. Rapid Development for Sensors for Novel Threat Agents | 164 |
| 13.5.3. Cross Correlation of Environmental Biological Sensors and Human Illness | 164 |
| 13.5.4. Facility Airborne Biological Toxin Alarm System (FABTAS) | 164 |
| 13.5.5. Field-Deployable Detection Technology for the Identification of Biological Toxins | 164 |
| 13.5.6. Forensics | 164 |
| 13.6. DARPA (DOD) – Biological Detection HLS Technologies R&D Programs | 165 |
| 13.6.1. Handheld Isothermal Silver Standard Sensor (HISSS) | 165 |
| 13.6.2. Triangulation Identification for Genetic Evaluation of Biological Risk (TIGER) | 165 |
| 13.6.3. Spectral Sensing of Bio-Aerosols (SSBA) | 166 |
| 13.6.4. Threat Agent Cloud Tactical Intercept Countermeasure (TACTIC) | 166 |
| 13.6.5. Immune Buildings | 167 |
| 13.7. CBDP (DOD) – Biological Detection HLS Technologies R&D Programs | 168 |
| 13.7.1. Project CB1 – Biological Defense (Basic Research) – Detection | 168 |
| 13.7.2. Project CB2 – Biological Defense (Applied Research) – Detection | 168 |
| 13.7.3. Project CB3 – Biological Defense (ATD) – Detection | 168 |
| 13.7.4. Project CA5 Contamination Avoidance (SDD) | 168 |
| 13.8. TSWG – Biological Detection HLS Technologies R&D Programs | 170 |
| 13.8.1. Real-Time Biological Aerosol Detection | 170 |
| 14. Bio-Detection Pricing Outlook – 2010-2014 | 171 |
| 15. Bio-Detection – Economic Considerations | 172 |
| 15.1. Overview | 172 |
| 15.2. Economical Analysis – Assumptions | 173 |
| 15.2.1. Bio-Detection – Economic Analysis | 173 |
| 15.2.2. Cost of Equipment Ownership | 173 |
| 15.2.3. Cost of Personnel/Year | 173 |
| 15.2.4. Cost of Test | 173 |
| 16. Bio-Detection – Personnel Considerations | 174 |
| 16.1. Background – Personnel | 174 |
| 16.2. Personnel Training | 174 |
| 17. Bio-Detection – Vendors and Products | 176 |
| 17.1. Bio Detection Samplers and Products | 176 |
| 17.2. Bio Detection Kits – Vendors and Products | 181 |
| 17.3. Bio Detection Screening Devices – Vendors and Products | 183 |
| 18. Appendix A: The Threat of Bioterror | 186 |
| 18.1. Use of Bioweapons – Historical Perspective | 187 |
| 18.2. Biological Terror – Bacterial Agents | 188 |
| 18.2.1. Anthrax | 189 |
| 18.2.2. Cholera | 190 |
| 18.2.3. Plague | 191 |
| 18.2.4. Tularemia | 192 |
| 18.3. Biological Terror – Viral Agents | 192 |
| 18.3.1. Smallpox | 193 |
| 18.3.2. Hemorrhagic Fever Viruses | 194 |
| 18.3.3. Venezuelan Equine Encephalitis | 196 |
| 18.4. Biological Terror – Rickettsiae Agents | 197 |
| 18.4.1. Q Fever | 197 |
| 18.4.2. Typhus | 198 |
| 18.5. Biological Terror – Toxins | 199 |
| 18.5.1. Botulinum Toxin | 199 |
| 18.5.2. Ricin | 200 |
| 18.5.3. Saxitoxin | 200 |
| 18.5.4. Staphylococcal Enterotoxin B (SEB) | 201 |
| 19. Appendix B: Bio-Detection – Patent Review | 202 |
| 19.1. Scope | 202 |
| 19.2. Bio-Detection Patents | 202 |
| 20. Appendix C: Legal Issues | 215 |
| 20.1. International / European Legislation / Agreements | 215 |
| 20.1.1. The Biological and Toxin Weapons Convention (BTWC) 1972 | 215 |
| 20.2. U.S. Bioterrorism Legislation | 220 |
List of Tables
| Table 1 – HLS & Defense Bio-Detection Systems and Service Market [$M] 2008 & 2014 – by Product Classification |
| Table 2 – Federal HLS-HLD Bio-Defense Funding [$Million] – FY2001-FY2009 |
| Table 3 – U.S. HLS Bio-Detection Systems and Service Market Forecast [$ Million] – 2010-2014 |
| Table 4 – U.S. HLS Bio-Detection Systems & Service (S&S) Market Forecast by Expenditure Share [%] – 2010-2014 |
| Table 5 – U.S. HLS Bio-Detection Systems & Service Market Forecast by Portability [$ Million] – 2010-2014 |
| Table 6 – U.S. HLS Bio-Detection Systems & Service Market Forecast by Modality Share [%] – 2010-2014 |
| Table 7 – Bio-Detection Systems Sales by Generation [$ Million] – 2010-2014 |
| Table 8 – Bio-Detection Systems Sales by Generation [%] – 2010-2014 |
| Table 9 – Bio-Detection Service and Upgrade Business Forecast by Technology Generation [$ Million] – 2010-2014 |
| Table 10 – Bio-Detection Service and Upgrade Business Forecast by Technology Generation Share [%] – 2008-2014 |
| Table 11 – U.S. Federal HLS-HLD Bio-Defense Funding [$ Millions], by Agency – FY2001-FY2009 |
| Table 12 – Comparison of Attributes of Bio-Detection Technologies |
| Table 13 – Bio-Detection Systems Sales by Generation [$ Million] – 2010-2014 |
| Table 14 – Bio-Detection Systems Sales by Generation Share [%] – 2010-2014 |
| Table 15 – Bio-Detection Consolidated Sales by Modality [$M] – 2010-2014 |
| Table 16 – Bio-Detection Systems Sales by Modality Share [%] – 2010-2014 |
| Table 17 – Bio-Detection Systems Quantity Sales by Generation [Units] – 2010-2014 |
| Table 18 – Bio-Detection Systems Quantity Sales by Generation Share [%] – 2010-2014 |
| Table 19 – Bio-Detection Systems Quantity Sales by Modality [Units] – 2010-2014 |
| Table 20 – Bio-Detection Systems Quantity Sales by Modality Share [%] – 2010-2014 |
| Table 21 – Bio-Detection Systems Installed Base by Generation [Units] – 2010-2014 |
| Table 22 – Bio-Detection Systems Installed Base Share [%] by Generation – 2010-2014 |
| Table 23 – Bio-Detection Systems Installed Base by Modality [Units] – 2010-2014 |
| Table 24 – Bio-Detection Systems Installed Base by Modality Share [%] – 2010-2014 |
| Table 25 – Outdoor Standoff Detectors Systems Sales by Generation [$ Million] – 2010-2014 |
| Table 26 – Outdoor Standoff Detectors Systems Sales by Generation Share [%] – 2010-2014 |
| Table 27 – Outdoor Standoff Detectors Systems Sales [Units] – 2010-2014 |
| Table 28 – Outdoor Standoff Detectors Systems Sales Share [%] – 2010-2014 |
| Table 29 – Outdoor Standoff-Detectors Systems Installed Base [Units] – 2010-2014 |
| Table 30 – Outdoor Standoff-Detectors Systems Installed Base Units Share [%] – 2010-2014 |
| Table 31 – Indoor Standoff Detectors Systems Sales by Generation [$M] – 2010-2014 |
| Table 32 – Indoor Standoff Detectors Systems Sales by Generation Share [%] – 2010-2014 |
| Table 33 – Indoor Standoff Detectors Systems Sales by Generation [Units] – 2010-2014 CAGR |
| Table 34 – Indoor Standoff Detectors Systems Sales by Generation Share [%] – 2010-2014 |
| Table 35 – Indoor Standoff-Detectors Systems Installed Base by Generation [Units] – 2010-2014 |
| Table 36 – Indoor Standoff-Detectors Systems Installed Base by Generation Share [%] – 2010-2014 |
| Table 37 – Point-Detectors Installed Base Systems by Modality [Thousand of Units] – 2010-2014 |
| Table 38 – First Responder Hand-Held Detection Systems Sales [$M] by Generation – 2010-2014 |
| Table 39 – First Responder Hand-Held Detection Systems Sales by Generation Share [%] – 2010-2014 |
| Table 40 – First Responder Hand-Held Detection Systems Sales [Units] by Generation – 2010-2014 |
| Table 41 – First Responder Hand-Held Detection Systems Sales by Generation Share [%] – 2010-2014 |
| Table 42 – First Responder Hand-Held Detection Systems Installed Base by Generation [Units] – 2010-2014 |
| Table 43 – First Responder Hand-Held Detection Systems Installed Base by Generation Share [%] – 2010-2014 |
| Table 44 – First Responder Mobile Labs Sales by Generation [$M] – 2010-2014 |
| Table 45 – First Responder Mobile Labs Sales by Generation Share [%] – 2010-2014 |
| Table 46 – First Responder Mobile Labs Sales by Generation [Units] – 2010-2014 |
| Table 47 – First Responder Mobile Labs Unit Sales by Generation Share [%] – 2010-2014 |
| Table 48 – First Responder Mobile Labs Installed Base by Generation [Units] – 2010-2014 |
| Table 49 – First Responder Mobile Labs Units Installed Base by Generation Share [%] – 2010-2014 |
| Table 50 – Bio-Detection Service & Upgrade Business Forecast by Modality [$M] – 2010-2014 |
| Table 51 – Bio-Detection Service & Upgrade Business Forecast by Modality Share [%] – 2010-2014 |
| Table 52 – Bio-Detection – Service Business Forecast by Technology Generation [$M] – 2010-2014 |
| Table 53 – Bio-Detection Service Business Forecast by Technology Generation Share [%] – 2010-2014 |
| Table 54 – Bio-Defense R&D Federal Funding by Agency [$ Million] – 2010-2014 |
| Table 55 – Bio Detection Samplers – Vendors and Products |
| Table 56 – Bio Detection Kits – Vendors and Products |
| Table 57 – Bio-Detection Screening Devices – Vendors and Products |
List of Figures
| Figure 1 – Types of Biological Detectors |
| Figure 2 – HLS & Defense Bio-Detection Systems and Service Market [$M] 2008 & 2014 – by Product Classification |
| Figure 3 – Bio-Detection Strategy – Three Pillars Diagram |
| Figure 4 – U.S. Government HLS-HLD Bio-Defense Funding [$ Million] – FY2001-FY2009 |
| Figure 5 – U.S. HLS Bio-Detection Systems & Service Market Forecast [$ Million] – 2010-2014 |
| Figure 6 – U.S. HLS Bio-Detection Systems & Service Market Share [%] – 2008, 2011 & 2014 |
| Figure 7 – U.S. HLS Bio-Detection Systems & Service Market Forecast by Modality [$ Million] – 2010-2014 |
| Figure 8 – U.S. HLS Bio-Detection Systems & Service Market Forecast by Modality Share [%] – 2008, 2011 & 2014 |
| Figure 9 – Bio-Detection Systems Sales by Generation [$ Million] – 2010-2014 |
| Figure 10 – Bio-Detection Service Business Forecast by Technology Generation [$ Million] – 2010-2014 |
| Figure 11 – Cumulative 2001-2009 Bio-Defense Funding [$Million], by Agency |
| Figure 12 – Bio-Defense Funding Share [%], by Agency – 2001, 2004 & 2009 |
| Figure 13 – Comparison in Weight of Pathogens Between BW Agents and CW Agents [mg] |
| Figure 14 – Typical Point Detection Automated Architecture (With a Combined Trigger/Cue) |
| Figure 15 – Airborne Bacterial Concentration Fluctuation in a Single Day |
| Figure 16 – Cross-Section of Cascade Impactor: PIXE International Corporation |
| Figure 17 – TSI’s Model 3317 System with Concentrator, GPS Receiver & Wireless Data Radio |
| Figure 18 – Biological Detection Technologies – 2010-2014 |
| Figure 19 – Flow Cytometry |
| Figure 20 – Gas Chromatography |
| Figure 21 – Polymerase Chain Reaction |
| Figure 22 – RT–PCR |
| Figure 23 – Principles of Real-Time PCR |
| Figure 24 – DNA Microarrays – Principles of Operation |
| Figure 25 – Schematic for Antibody Protein |
| Figure 26 – Hand Held Detectors: Alexeter Guardian Reader System and Tetracore Test Strips |
| Figure 27 – Roche Applied Science – Light CyclerTM Model 1.2 |
| Figure 28 – Bio-Detection Systems Sales by Generation [$M] – 2010-2014 |
| Figure 29 – Bio-Detection Systems Sales by Generation Share [%] – 2008, 2011 & 2014 |
| Figure 30 – Bio-Detection Systems Sales by Modality [$M] – 2010-2014 |
| Figure 31 – Bio-Detection Systems Sales by Modality Share [%] – 2008, 2011 & 2014 |
| Figure 32 – Bio-Detection Systems Quantity Sales by Generation [Units] – 2010-2014 |
| Figure 33 – Bio-Detection Systems Quantity Sales by Generation Share [%] – 2008, 2011 & 2014 |
| Figure 34 – Bio-Detection Systems Quantity Sales by Modality [Units] – 2010-2014 |
| Figure 35 – Bio-Detection Systems Quantity Sales by Modality Share [%] – 2008, 2011 & 2014 |
| Figure 36 – Bio-Detection Systems Installed Base by Generation [Units] – 2010-2014 |
| Figure 37 – Bio-Detection Systems Installed Base Share [%] by Generation – 2008, 2011 & 2014 |
| Figure 38 – Bio-Detection Systems Installed Base by Modality [Units] – 2008-2014 |
| Figure 39 – Bio-Detection Systems Installed Base by Modality Share [%] – 2008, 20011 & 2014 |
| Figure 40 – Outdoor Systems Standoff Detectors Sales by Generation [$M] – 2010-2014 |
| Figure 41 – Outdoor Standoff Detectors Systems Sales by Generation Share [%] – 2008, 2011 & 2014 |
| Figure 42 – Outdoor Standoff Detectors Systems Sales [Thousand of Units] – 2010-2014 |
| Figure 43 – Outdoor Standoff Detectors Systems – Sales Share [%] – 2008, 2011 & 2014 |
| Figure 44 – Outdoor Standoff-Detectors Systems Installed Base Units Share [Units] – 2010-2014 |
| Figure 45 – Outdoor Standoff Detectors Systems Installed Base Share [%] – 2008, 2011 & 2014 |
| Figure 46 – Indoor Standoff Detectors Systems Sales by Generation [$M] – 2010-2014 |
| Figure 47 – Indoor Standoff Detectors Systems Sales by Generation Share [%] – 2008, 2011 & 2014 |
| Figure 48 – Indoor Standoff Detectors Systems Unit Sales by Generation [Units] – 2010-2014 |
| Figure 49 – Indoor Standoff Detectors Systems Sales by Generation Share [%] – 2008, 2011 & 2014 |
| Figure 50 – Indoor Standoff-Detectors Systems Installed Base by Generation [Units] – 2010-2014 |
| Figure 51 – Indoor Standoff Detectors Systems Installed Bases by Generation Share [%] – 2008, 2011 & 2014 |
| Figure 52 – Point-Detectors Installed Base Systems Share by Modality [%] – 2008, 2011 & 2014 |
| Figure 53 – First Responder Hand-Held Detection Systems Sales [$M] by Generation – 2010-2014 |
| Figure 54 – First Responder Hand-Held Detection Systems Sales by Generation Share [%] – 2008, 2011 & 2014 |
| Figure 55 – First Responder Hand-Held Detection Systems Sales by Generation [Units] – 2010-2014 |
| Figure 56 – First Responder Hand-Held Detection Systems Sales by Generation Share [%] – 2008, 2011 & 2014 |
| Figure 57 – First Responder Hand-Held Detection Systems Installed Base by Generation [Units] – 2010-2014 |
| Figure 58 – First Responder Hand-Held Detection Systems Installed Base by Generation Share [%] – 2008, 2011 & 2014 |
| Figure 59 – First Responder Mobile Labs Sales by Generation [$M] – 2010-2014 |
| Figure 60 – First Responder Mobile Labs Sales by Generation Share [%] – 2008, 2011 & 2014 |
| Figure 61 – First Responder Mobile Labs Sales by Generation [Units] – 2010-2014 |
| Figure 62 – First Responder Mobile Labs Unit Sales by Generation Share [%] – 2008, 2011 & 2014 |
| Figure 63 – First Responder Mobile Labs Unit Installed Base by Generation Share [Units] – 2010-2014 |
| Figure 64 – First Responder Mobile Labs Installed Base by Generation Share [%] – 2008, 2011 & 2014 |
| Figure 65 – Bio-Detection Service & Upgrade Business Forecast by Modality [$M] – 2010-2014 |
| Figure 66 – Bio-Detection Service & Upgrade Business Forecast by Modality Share [%] – 2008, 2011 & 2014 |
| Figure 67 – Bio-Detection Service & Upgrade Business Forecast by Technology Generation [$M] – 2010-2014 |
| Figure 68 – Bio-Detection Service & Upgrade Business Forecast by Technology Generation [%] – 2008, 2011 & 2014 |
| Figure 69 – Factors Affecting Biological Detection Deployment and Technologies – 2010-2014 |
| Figure 70 – Bio-Detection Timeline |
| Figure 71 – Civilians in China During the SARS Epidemic |
| Figure 72 – A Typical Microfluidic Device |
| Figure 73 – Bio-Defense R&D Federal Funding by Agency [$ Million] – 2010-2014 |
| Figure 74 – DHS Bio-Security R&D Budget Forecast [$ Million] – 2010-2014 (Without Bio-Shield Funding) |
| Figure 75 – DOD Biosecurity R&D Budget Forecast [$ Million] – 2010-2014 (Without BioShield Funding) |
| Figure 76 – DHHS Bio-security R&D Budget Forecast [$ Million] – 2010-2014 |
| Figure 77 – Other Agencies Biosecurity R&D Budget Forecast [$ Million] – 2010-2014 |
| Figure 78 – The Spraying of Anthrax from Aum Shinrikyo’s Headquarters June 1993 |
| Figure 79 – Anthrax Spores and Disease |
| Figure 80 – Cholera Bacteria |
| Figure 81 – Pneumonic Plague – The Disease |
| Figure 82 – Tularemia – The Disease |
| Figure 83 – Smallpox Virus And Disease |
| Figure 84 – Ebola Virus – Electron Microscopy Image |
| Figure 85 – VEE – Venezuelan Equine Encephalitis Virus in the Olfactory Mucosa of a Mouse |
| Figure 86 – Q Fever |
| Figure 87 – Typhus Microbe – Electron Microscopy Image |
| Figure 88 – Castor Plant And Structure For The Ricin Toxin |
| Figure 89 – The Dinoflagellate Alexandrium Tamarense And Structure of Saxitoxin |
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